Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.
Langerin is required for the biogenesis of Birbeck granules (BGs), the characteristic organelles of Langerhans cells.We previously used a Langerin-YFP fusion protein having a C-terminal luminal YFP tag to dynamically decipher the molecular and cellular processes which accompany the traffic of Langerin.In order to elucidate the interactions of Lange